Monoklonal gammopati af ukendt signifikans kan medføre polyneuropati og oftalmoplegi

Publication: Research - peer-reviewJournal article

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Translated title of the contributionA syndrome of chronic ataxic polyneuropathy, ophtalmoplegia, IgM paraprotein, cold agglutinins and anti-disialosyl antibodies can cause diplopia in patients with chronic sensory polyneuropathy
CANOMAD is a rare syndrome of chronic ataxic polyneuropathy, ophtalmoplegia, IgM paraprotein, cold agglutinins and anti-disialosyl antibodies. We present a case of a 65-year-old woman with clinical and electrophysiological features of chronic sensory polyneuropathy and diplopia. Serum samples from the patient contained IgM paraprotein and anti-GM2-antibodies. Treatment with intravenous immunoglobulins resulted in an improvement of the patient's diplopia and polyneuropathy. The case shows the importance of considering CANOMAD as a cause of diplopia in patients with chronic sensory polyneuropathy.
Original languageDanish
JournalUgeskrift for Laeger
Volume174
Issue number43
Pages (from-to)2635-6
Number of pages2
ISSN0041-5782
StatePublished - 2012
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