Exercise reduces adipose tissue via cannabinoid receptor type 1 which is regulated by peroxisome proliferator-activated receptor-delta

Research output: Contribution to journalJournal articleResearchpeer-review

  • Zhen Cheng Yan
  • Dao Yan Liu
  • Li Li Zhang
  • Chen Yi Shen
  • Qun Li Ma
  • Ting Bing Cao
  • Li Juan Wang
  • Hai Nie
  • Walter Zidek
  • Martin Tepel
  • Zhi Ming Zhu

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Obesity is one major cardiovascular risk factor. We tested effects of endurance exercise on cannabinoid receptor type 1 (CB1) and peroxisome proliferator-activated receptor-delta (PPAR-delta)-dependent pathways in adipose tissue. Male Wistar rats were randomly assigned to standard laboratory chow or a high-fat diet without and with regular endurance exercise. Exercise in rats on high-fat diet significantly reduced visceral fat mass, blood pressure, and adipocyte size (each p
LanguageEnglish
JournalBiochemical and Biophysical Research Communications
Volume354
Issue number2
Pages (from-to)427-33
Number of pages7
ISSN0006-291X
DOIs
StatePublished - 2007

    Research areas

  • 3T3 Cells, Adipose Tissue, Animals, Disease Models, Animal, Male, Metabolic Syndrome X, Mice, Obesity, PPAR delta, Physical Conditioning, Animal, Rats, Rats, Wistar, Receptor, Cannabinoid, CB1