Genetic association studies in lumbar disc degeneration: a systematic review

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  • Pasi J Eskola
  • Susanna Lemmelä
  • Per Kjær
  • Svetlana Solovieva
  • Minna Männikkö
  • Niels Tommerup
  • Allan Lind-Thomsen
  • Kirsti Husgafvel-Pursiainen
  • Kenneth M C Cheung
  • Danny Chan
  • Dino Samartzis
  • Jaro Karppinen

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Low back pain is associated with lumbar disc degeneration, which is mainly due to genetic predisposition. The objective of this study was to perform a systematic review to evaluate genetic association studies in lumbar disc degeneration as defined on magnetic resonance imaging (MRI) in humans.
JournalP L o S One
Issue number11
Pages (from-to)e49995
Publication statusPublished - 21 Nov 2012